With miles and miles of the Ohio River winding its way through the hilly landscape and nearly 60,000 acres of the Hoosier National Forest, Perry County in Southern Indiana is a delight for outdoor enthusiasts as well as wine lovers following the Uplands Wine Trail.

The river towns of Perry County are a stop on the 981-mile Ohio River Scenic Route that passes through six states and was designated a National Scenic Byway in 1996, a distinction held by other notable routes like the Blue Ridge Parkway, the Natchez Trace and the Pacific Highway

West from Derby, a lovely bend on the water with cabins and boat rentals available, the road follows the river through Cannelton with its old cotton mill, now a National Historic Landmark which, when it was built in 1849, was the largest industrial building west of the Alleghenies.